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The intended final sample size was 60 patients (20 per site) for each Phase Group, and 30 healthy controls (10 per site) age matched to each of the patient groups giving a planned total sample of 180

MDSCs play a pivotal role in maintaining immune tolerance and preventing excessive immune responses (82)

Conclusion The development of antibiotic resistance in bacterial pathogens is particularly alarming and is one of the biggest challenges to healthcare facilities worldwide

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This practice, which is truly evidence-based and promotes the steady reduction in tissue urate crystal deposits, is promoted by the ACR, EULAR and 3e Initiative recommendations